Promotes optimal prostate health*
Supports healthy bladder function*
Saw Palmetto
Saw palmetto is an herb native to North America
whose ripe fruits have been traditionally used by Native American communities
for hundreds of years to support the health of the urinary tract and related
systems. The first observations of the therapeutic applications of this herb
appeared in the American Journal of Urology in 1892. Research has confirmed that
saw palmetto may possess activity at a multitude of levels in the urinary
system, including direct effects on the prostate gland and urinary bladder.1
Saw palmetto berry is also listed in the German Commission E monographs as an
approved herb for its ability to support healthy urinary and prostate function.2
A number of clinical studies have shown beneficial results with the consumption
of a standardized extract of saw palmetto. In one double-blind,
placebo-controlled trial of 110 individuals, supplementation of 160 mg of saw
palmetto standardized extract twice daily significantly benefited various
urinary flow measures as well as participant and physician self-ratings of
improvement. A second double-blind study also demonstrated an enhancement of
urinary function and flow in 43% of those taking the saw palmetto extract versus
the same enhancements seen in only 15% of those taking a placebo.3
A further double-blind, placebo-controlled study was conducted in men to assess
the effects of saw palmetto (160 mg twice per day, standardized to 85-95% fatty
acids), or a placebo, on urination and related measures. The supplements were
given to 85 men aged 45 or older for 6 months. The results of the study showed
that saw palmetto was able to support urinary function to a significantly
greater degree than the placebo.4
Numerous well-designed studies have been performed over the years highlighting
the positive benefits of saw palmetto supplementation on prostate and urinary
wellness. Saw palmetto is recognized for its efficacy in supporting these
systems.*
Crateva nurvala
Crateva nurvala is an ancient herb used for generations in the traditional
Indian system of medicine known as Ayurveda. Ancient
Ayurvedic practitioners used it as an internal purifier that helped maintain
homeostasis and balance. This herb has a long
history of use as the herb of choice to maintain healthy urinary tract and
bladder function. The tree that is the source of
this herb is often found growing along the banks of rivers in the sub-Himalayan
regions of India.
The stem bark is the part used to benefit urinary health.5
Studies with Crateva nurvala have been conducted in
India demonstrating the herb’s efficacy in
maintaining healthy urinary bladder function. Animal
studies with the water extract of Crateva have shown that the herb has the
ability to increase the tone of smooth muscle and skeletal muscle.
In a rat model of kidney stones, researchers were able to show that rats
given Crateva extract had significantly smaller stones than in the untreated
group.6 In addition, a study conducted in dogs showed that the
animals receiving Crateva extract for 40 days had significantly higher
maintenance of bladder tone than control animals.7
A tea prepared from the bark of the plant was given to 30 individuals (50 ml
twice daily). Baseline measures of urinary function
and bladder tone were assessed at the beginning of the study.
It was found that when compared to baseline, the Crateva tea showed a
high ability to promote healthy urinary function and enhance bladder tone in
these individuals after 3 months of use.7
Equisetum arvense
Equisetum arvense, also known as horsetail, is a traditional plant that is
especially rich in silica and other essential minerals.
It is a member of a prehistoric family of plants that is now one of the
most common species in northern temperate climates.
In addition to being extremely rich in the mineral silica, horsetail also
contains saponins and flavonoids. The combination of
these constituents is thought to be responsible for its beneficial properties.8
Traditional cultures have used horsetail over the years for its various healing
properties. Traditional herbalists recommended horsetail for healing wounds
because of its noticeably astringent effects.
Internally, horsetail was used to promote healthy digestive function.9
Because of its flavonoid, saponin and mineral content, horsetail has a special
affinity for the urinary tract. Its tonic and
astringent properties were used to promote healthy urinary bladder function and
to strengthen urinary sphincter control.10 The German Commission E
monograph on horsetail also supports its use for maintaining the health of the
urinary tract.2
Lycopene (from Tomato fruit)
Tomatoes are a rich source of the carotenoid lycopene, Lycopene has been shown
to possess potent antioxidant activity in vitro. The intake of lycopene-rich
foods has also been shown to be supportive of healthy prostate function.11
Lycopene intake was also studied in a crossover trial in women supplemented with
a diet containing a tomato puree, or a tomato-free diet, for 21 days. Plasma
lycopene concentrations increased in the subjects supplemented with the puree,
while levels decreased in the non-supplemented group. Blood samples were taken
from both groups to determine the antioxidant effect of lycopene on lymphocyte
DNA damage. The results showed that the two groups supplemented with tomato
puree in their diet had 42% and 33% less lymphocyte DNA damage than the
non-supplemented group, showing a significant antioxidant effect of lycopene.12
Lycopene may act through a variety of mechanisms to support prostate gland
health. Some of these include as a highly efficient scavenger of oxygen
radicals, conferring protection to lipids, proteins and DNA from oxidation;
enhancement and facilitation of cell-to-cell communication, supporting the
exchange of nutrients and signaling molecules between cells; promotion of
antioxidative enzyme activity, including glutathione peroxidase,
glutathione-S-transferase, and glutathione reductase enzyme activity, while also
increasing glutathione levels.13 These findings suggest that lycopene
may have the ability to support healthy prostate function via a multi-faceted
approach.
Zinc and Selenium
Best Prostate & Bladder Support featuring UroLogicProsÔ
is also fortified with the essential minerals zinc and selenium.
These minerals play a critical part in supporting the health of prostate
gland cells. Zinc is present normally in much higher
concentrations (up to 10 times more) in the prostate gland than in any other
body organ. Zinc helps to maintain healthy prostate function by normalizing the
activity of enzymes and modulating and balancing levels of certain hormones
involved in the regulation of prostatic function. Zinc is also essentially
involved in supporting overall immune health.14
Selenium is a mineral that serves as a cofactor for a number of enzymes and has
potent antioxidant effects in various tissues. Research has shown that selenium,
through its free radical scavenging abilities, can regulate the healthy function
of prostate cells. Studies also suggest that selenium may enhance immune
function. Evidence suggests that higher plasma levels of selenium may lead to
healthier prostate function (Haojie et al. 2004).15
Both of these minerals are essential for prostate health and the dietary intakes
of these nutrients tend to be low in various regions throughout the
US. The soil in which crops are grown is often
deficient in one or both nutrients and the increased consumption of processed
foods also contributes to this trend.
Research on UroLogicPros™
A clinical study has been conducted on UroLogicPros™ in
Australia
by Applied Science and Nutrition Research on behalf of Biologic Health Solutions
Pty. Ltd., the developers of the formulation. In this trial, 39 men were
recruited and 33 of the participants (with an age range between 39 and 78 years)
completed the study. The 3-month experiment was designed to assess the ability
of UroLogicPros™ to support parameters of healthy urinary and prostate function.
UroLogicPros™ was supplemented regularly at the recommended daily dose. The
results showed significant and progressive benefits of UroLogicPros™
supplementation on the urinary parameters assessed over the three-month study
period. Similar progressive benefits were also noted on questionnaires designed
to measure prostate function. Assessment was made at baseline and then at the
end of month 1, 2 and 3.16 The results of this study clearly showed
that UroLogicPros™ has the ability to enhance prostate health and support
healthy urinary function in this study population.
Best Prostate
and Bladder Support featuring UroLogicPros™ combines the powerful
prostate-supportive herb Saw palmetto with the potent combination of the herbs
Crateva nurvala and Horsetail to support healthy urinary bladder function. The
formula is further fortified with the added antioxidant, immune-enhancing and
prostate-specific benefits of the essential nutrients lycopene, zinc, and
selenium. The combination of the herbs and nutrients in Best Prostate and
Bladder Support work synergistically to provide essential, clinically-tested
support for prostate health and bladder function.*