Endothelial Defense With Full-Spectrum Pomegranate
The vascular endothelium is the inner lining of blood vessels that regulates
arterial and venous health. The reason for many circulatory problems is the
breakdown of endothelial function and structure. Fortunately, there are
nutrients that have been clinically shown to help maintain healthy endothelial
function and arterial circulation.
Pomegranate promotes cardiovascular health
In a group of aging humans with risk factors for cardiovascular events,
pomegranate or a placebo was ingested daily. Both groups continued taking their
conventional medications. After twelve months, carotid artery conditions
(measured as carotid intima-media thickness) were improved 30% in the
pomegranate group while carotid artery conditions worsened by 9% in the placebo
group.38 Additionally, in those who consumed pomegranate, total antioxidant
status was increased by 130% while blood serum levels of LDL basal oxidative
state and LDL susceptibility to oxidation were both significantly reduced by 90%
and 59% respectively.
In a similar study, pomegranate or a placebo was ingested daily. After only
three months, coronary artery blood flow improved by 18% in the pomegranate
group but worsened by 17% in the placebo group.39
A next-generation pomegranate extract, blending standardized extracts from the
whole fruit, flower and seed oil, is one of the active components of Endothelial
Defense™ formula. Full-Spectrum Pomegranate™ provides this fruit’s unique
polyphenols with newly discovered biologically active compounds from other parts
of the pomegranate plant.
SOD protects against nitric oxide degradation
Aging reduces the body’s production of a critical antioxidant called superoxide
dismutase (SOD), which provides the body’s first enzymatic step in the defense
system against oxidative stress. Diminished SOD levels are closely linked with
increased vascular oxidative stress, which contributes to endothelial
dysfunction.46 An orally active superoxide dismutase (SOD) called GliSODin® has
been clinically shown to support healthy arterial function and structure, while
boosting levels of the body’s most powerful antioxidant enzymes (SOD and
catalase) and protecting against oxidative stress-induced cell death.47-50
Studies show that carotid artery thickness detrimentally increases by 0.04 mm
every ten years. However, a recent study with GliSODin® suggests that 2.8 years
of supplementation may turn back the clock on 10 years of age-related damage due
to carotid artery wall thickening.51 Endothelial Defense™ formula contains
GliSODin® in a dose identical to that which was used in this successful human
Endothelial Defense™ provides the best-documented nutrients to help you maintain
healthy arterial blood flow and normal blood pressure
Dosage and Use
: Take two
softgels daily before breakfast, or as recommended by a healthcare practitioner.
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please consult with your physician if you
are undergoing treatment for a medical condition or if you are pregnant or
Serving Size 2 softgels
Servings Per Container 30
Amount Per Serving
Superoxide Dismutase/Gliadin Complex (GliSODin®) [SOD (Superoxide
Dismutase) Enzyme Activity = 500 IU]
POMELLA® Pomegranate (Punica granatum) Extract (fruit) [std. to 30%
punicalagins (120 mg)]
Pomegranate (Punica granatum) 5:1 Extract (fruit)
PomComplete™ Pomegranate (Punica granatum) Blend [flower extract and
seed oil (standardized to 22% (30 mg) punicic acid)]
Other ingredients: soybean oil, maltodextrin, gelatin, glycerin,
purified water, caramel color, beeswax, phosphatidylcholine.
Contains soybeans and wheat. Contains gluten.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish
(lobster, crab, shrimp), tree nuts, yeast, corn or rice. Contains NO
artificial sweeteners, flavors, colors, or preservatives.