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Grape Seed (Vitis Vinifera). Polyphenols
(previously called bioflavonoids) found in grape seed extract protect
the heart and promote healthy veins, arteries and capillaries. An
important subgroup of polyphenols in grape seed are leucoanthocyanins or
proanthocyanidins. These flavonoids help to strengthen blood vessels,
increasing the tone and elasticity of capillary walls, enhance the
effect of vitamin C, and help to quench free radicals. That is why Grape
seed leucoanthocyanins or proanthocyanidins may be useful in a number of
disorders. They improve the biochemical properties of blood vessels, and
help different types of vascular disorders including capillary
fragility, peripheral chronic venous insufficiency and microangiopathy
of the retina.
Grape Seed may help allergy sufferers because the leucoanthocyanins
exert an inhibiting effect on histamine release, suppressing allergy
Grape Seed has been shown to be helpful against mild and severe
artherosclerosis when rabbits were fed a cholesterol-rich diet. It also
helped to protect rabbit heart against ischemica/reperfusion injury.
Grape Seed is standardized to contain 85 to 95% leucoanthocyanins
(proanthocyanidins), bound to phosphatidylcholine from lecithin.