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Home > Supplements > Antioxidants >
High Absorption CoQ10 contains pure, vegetarian source
Coenzyme Q10 in a base of rice powder, plus Bioperine®, an herbal
extract that enhances CoQ10 absorption.
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Boosts Cellular Energy Production*
Coenzyme Q10 is a vitamin-like nutrient found in the human body.
Essential to life, CoQ10 works at the cellular level to produce
metabolic energy in the form of ATP.*1,2
CoQ10 serves as a vital link in the "electron transport chain," which
is the final step in the production of ATP inside cells. Lacking
adequate CoQ10, cells become energy-deficient. When cells are nourished
with optimal levels of CoQ10, tissues, organs and systems function
optimally.
Strengthens and Protects the Heart*
The heart is the hardest-working muscle in the body. Because of its high
energy requirements, the heart needs to be well supplied with CoQ10 at
all times. The body's highest concentration of CoQ10 occurs in heart
muscle tissue. (Heart muscle cells contain large numbers of
mitochondria.) Numerous clinical studies have demonstrated significant
improvements in heart function with oral administration of CoQ10.3,4,5
Supports Immune Function*
When the immune system goes into battle for us, immune cells need large
amounts of energy to carry out their defensive functions. CoQ10 is
required for this energy to be available. Experimental research on
animals has shown that CoQ10 enhances immune functions such as the
activity of phagocytes, and antibody production.* Age-related immune
suppression has been observed in mice given CoQ10.6
Antioxidant Protection
CoQ10 is a versatile antioxidant.* The reduced form of CoQ10,
ubiquinol-10, has been found to protect LDL against peroxidation by free
radicals more effectively than vitamin E.* CoQ10 stabilizes membranes,*
thus protecting them from free-radical damage.7,8,9
Benefits the Gums*
A number of studies have shown that CoQ10 supports repair of gingival
(gum) tissue. Gingival tissues in people with periodontal disease have
been found deficient in CoQ10. In several double-blind clinical trials,
oral administration of CoQ10 has resulted in significant improvements.10,11
Many Clinical Benefits
Research studies and clinical reports suggest CoQ10 has a broad range of
applications stemming from its ability to support the heart and
cardiovascular system, the immune system, cellular energy production,
liver function, nerves, and muscles.*
CoQ10 – Vitamin E's Partner
In vitro studies suggest CoQ10 in combination with vitamin E protects
LDL cholesterol from oxidation more effectively than vitamin E alone.
Protecting LDL from being oxidized by free radicals is now thought to be
important for cardiovascular health.9,12
Bioperine® – A Bioavailability-Enhancing Phytonutrient
Bioperine® is a natural extract derived from black pepper that enhances
nutrient absorption.* Preliminary trials on humans have shown
significant increases in the absorption of nutrients consumed along with
Bioperine®. In a recent study (publication pending), the administration
of 5 mg of Bioperine® together with 120 mg of CoQ10 per day resulted in
a 32% increase in CoQ10 absorption after 21 days.13 (This is especially important for individuals who have impaired
absorption of fat-soluble nutrients such as CoQ10.)
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Suggested Use: As a dietary supplement, take 1 capsule daily. For
maximum absorption, take with a fat-containing meal.
The black pepper fruit extract used in this product is Bioperine, a
patented standardized extract containing 95% piperine.
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1. Folkers, K., Wolaniuk, A., Progress in biomedical and clinical
research on coenzyme Q10. Drugs Exptl. Clin. Res. 1984; X(7):513-517.
2. Lenaz, G., et. al., "The essentially of coenzyme Q for bioenergetics
and clinical medicine." Drugs Exptl. Clin. Res. 1985; XI(8):547-556.
3. Morisco, C., Trimarco, B., Condorelli, M., "Effect of coenzyme Q10
therapy in patients with congestive heart failure: a long-term
multicenter randomized study." Clin. Investig. 1993; 71:S134-S136.
4. Mortensen, S.A., Vadhanavikit, S., Muratsu, K., Folkers, K.,
"Coenzyme Q10: clinical benefits with biochemical correlates suggesting
a scientific breakthrough in the management of chronic heart failure."
Int. J. Tiss Reac. 1990; XII(3):155-62.
5. Poggesi, L., et. al., Effect of coenzyme Q10 on left ventricular
function in patients with dilative cardiomyopathy. Current Therapeutic
Research 1991; 49(5):878-886.
6. Folkers, K., Wolaniuk, A., "Research on coenzyme Q10 in clinical
medicine and in immunomodulation." Drugs Exptl. Clin. Res. 1985;
XI(8):539-545.
7. Littarru, G.P., et. al., "In vitro effect of different ubiquinones on
the scavenging of biologically generated O2." Drugs Exptl. Clin. Res.
1985; XI(8):529-532.
8. Littarru, G.P. Lippa, S., "Coenzyme Q and antioxidant activity: facts
and perspectives." Drugs Exptl. Clin. Res. 1984; X(7):491-96.
9. Stocker, R., Bowry, V.W., Frei, B., "Ubiquinol-10 protects human low
density lipoprotein more efficiently against lipid peroxidation than
does alpha-tocopherol." Proc. Natl. Acad. Sci. 1991; 88:1646-1650.
10. Hansen, I., Iwamoto, Y., Kishi, T., Folkers, K., "Bioenergetics in
clinical medicine. IX. Gingival and leucocyte deficiencies of coenzyme
Q10 in patients with periodontal disease." Research Communications in
Chemical Pathology and Pharmacology 1976; 14:729-738.
11. Wilkinson, E. Arnold, R., Folkers, K., "Treatment of Periodontal and
Other Soft Tissue Diseases of the Oral Cavity with Coenzyme Q" (in)
Biomedical and Clinical Aspects of Coenzyme Q 1977; 1:251-266. K.
Folkers and Y. Yamaura, eds., Elsevier Science Publishing Co., N.Y.
12. Thomas, S., Neuzil, J., Stocker, R., "Cosupplementation with
coenzyme Q prevents the prooxidant effect of alpha-tocopherol and
increases the resistance of LDL to transition metal dependant oxidation
initiation." Arteriosclerosis, Thrombosis and Vascular Biology 1996;
16(5):687-96.
13. Badmaev, V., Majeed, M., "Comparison of Coenzyme Q10 (CoQ10)
bioavailability when ingested alone and in combination with Bioperine®."
Sabinsa Corporation Research Report. 1996 (unpublished). |
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