High Absorption CoQ10
contains pure, vegetarian source Coenzyme Q10 in a base of rice powder, plus
Bioperine®, an herbal extract that enhances CoQ10 absorption.

Benefits
Boosts Cellular Energy Production*
Coenzyme Q10 is a vitamin-like nutrient found in the human
body. Essential to life, CoQ10 works at the cellular level to produce metabolic
energy in the form of ATP.*1,2
CoQ10 serves as
a vital link in the "electron transport chain," which is the final step in the
production of ATP inside cells. Lacking adequate CoQ10, cells become
energy-deficient. When cells are nourished with optimal levels of CoQ10,
tissues, organs and systems function optimally.
Strengthens and Protects
the Heart*
The heart is the hardest-working muscle in the body.
Because of its high energy requirements, the heart needs to be well supplied
with CoQ10 at all times. The body's highest concentration of CoQ10 occurs in
heart muscle tissue. (Heart muscle cells contain large numbers of mitochondria.)
Numerous clinical studies have demonstrated significant improvements in heart
function with oral administration of CoQ10.3,4,5
Supports Immune Function*
When the immune system goes into battle for us,
immune cells need large amounts of energy to carry out their defensive
functions. CoQ10 is required for this energy to be available. Experimental
research on animals has shown that CoQ10 enhances immune functions such as the
activity of phagocytes, and antibody production.* Age-related immune suppression
has been observed in mice given CoQ10.6
Antioxidant Protection
CoQ10 is a versatile antioxidant.* The reduced
form of CoQ10, ubiquinol-10, has been found to protect LDL against peroxidation
by free radicals more effectively than vitamin E.* CoQ10 stabilizes membranes,*
thus protecting them from free-radical damage.7,8,9
Benefits the Gums*
A number of studies have shown that CoQ10
supports repair of gingival (gum) tissue. Gingival tissues in people with
periodontal disease have been found deficient in CoQ10. In several double-blind
clinical trials, oral administration of CoQ10 has resulted in significant
improvements.10,11
Many Clinical Benefits
Research studies and clinical reports suggest
CoQ10 has a broad range of applications stemming from its ability to support the
heart and cardiovascular system, the immune system, cellular energy production,
liver function, nerves, and muscles.*
CoQ10 – Vitamin E's
Partner
In vitro studies suggest CoQ10 in combination
with vitamin E protects LDL cholesterol from oxidation more effectively than
vitamin E alone. Protecting LDL from being oxidized by free radicals is now
thought to be important for cardiovascular health.9,12
Bioperine® – A
Bioavailability-Enhancing Phytonutrient
Bioperine® is a natural extract derived from
black pepper that enhances nutrient absorption.* Preliminary trials on humans
have shown significant increases in the absorption of nutrients consumed along
with Bioperine®. In a recent study (publication pending), the administration of
5 mg of Bioperine® together with 120 mg of CoQ10 per day resulted in a 32%
increase in CoQ10 absorption after 21 days.13
(This is especially important for individuals who have impaired absorption of
fat-soluble nutrients such as CoQ10.)
Safety
Suggested Use: As a
dietary supplement, take 1 softgel daily.
The black pepper
fruit extract used in this product is Bioperine®, a patented standardized
extract containing 95% piperine.
Does Not Contain: milk, egg, wheat, corn, sweeteners,
starch, salt, or preservatives.
Scientific
References
1. Folkers, K., Wolaniuk, A., Progress in biomedical and clinical research on
coenzyme Q10. Drugs Exptl. Clin. Res. 1984; X(7):513-517.
2. Lenaz, G., et. al., "The essentially of coenzyme Q for bioenergetics and
clinical medicine. "Drugs Exptl. Clin. Res. 1985; XI(8):547-556.
3. Morisco, C., Trimarco, B., Condorelli, M., "Effect of coenzyme Q10 therapy in
patients with congestive heart failure: a long-term multicenter randomized
study." Clin. Investig. 1993; 71:S134-S136.
4. Mortensen, S.A., Vadhanavikit, S., Muratsu, K., Folkers, K., "Coenzyme Q10:
clinical benefits with biochemical correlates suggesting a scientific
breakthrough in the management of chronic heart failure." Int. J. Tiss Reac.
1990; XII(3):155-62.
5. Poggesi, L., et. al., Effect of coenzyme Q10 on left ventricular function in
patients with dilative cardiomyopathy. Current Therapeutic Research 1991;
49(5):878-886.
6. Folkers, K., Wolaniuk, A., "Research on coenzyme Q10 in clinical medicine and
in immunomodulation." Drugs Exptl. Clin. Res. 1985; XI(8):539-545.
7. Littarru, G.P., et. al., "In vitro effect of different ubiquinones on the
scavenging of biologically generated O2." Drugs Exptl. Clin. Res. 1985;
XI(8):529-532.
8. Littarru, G.P. Lippa, S., "Coenzyme Q and antioxidant activity: facts and
perspectives." Drugs Exptl. Clin. Res. 1984; X(7):491-96.
9. Stocker, R., Bowry, V.W., Frei, B., "Ubiquinol-10 protects human low density
lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol."
Proc. Natl. Acad. Sci. 1991; 88:1646-1650.
10. Hansen, I., Iwamoto, Y., Kishi, T., Folkers, K., "Bioenergetics in clinical
medicine. IX. Gingival and leucocyte deficiencies of coenzyme Q10 in patients
with periodontal disease." Research Communications in Chemical Pathology and
Pharmacology 1976; 14:729-738.
11. Wilkinson, E. Arnold, R., Folkers, K., "Treatment of Periodontal and Other
Soft Tissue Diseases of the Oral Cavity with Coenzyme Q" (in) Biomedical and
Clinical Aspects of Coenzyme Q 1977; 1:251-266. K. Folkers and Y. Yamaura, eds.,
Elsevier Science Publishing Co., N.Y.
12. Thomas, S., Neuzil, J., Stocker, R., "Cosupplementation with coenzyme Q
prevents the prooxidant effect of alpha-tocopherol and increases the resistance
of LDL to transition metal dependant oxidation initiation." Arteriosclerosis,
Thrombosis and Vascular Biology 1996; 16(5):687-96.
13. Badmaev, V., Majeed, M., "Comparison of Coenzyme Q10 (CoQ10) bioavailability
when ingested alone and in combination with Bioperine®." Sabinsa Corporation
Research Report. 1996 (unpublished).