Scientists have identified specific biological mechanisms that cause
aging people to gain weight… no matter how little they eat. The problem
was that there was no way to circumvent the underlying factors that
cause excess body fat… until now! As you are about to learn, gaining
control over your body’s command signals is critical to maintaining a
Leptin is a hormone that tells our brain that we have consumed enough
calories and can stop eating. Leptin also induces a process whereby fat
stored in cells is broken down. As we age, our cells (including the
appetite control center in our brains) become “leptin resistant.” This
means that leptin is unable to effectively regulate body weight.
Adult-onset weight gain is characterized by the enlargement of
existing adipocytes (fat cells) that store too much fat. The size of
fat cells is controlled by gene transcription factors.
Fat cell size is closely related with adiponectin expression — with
reduced adiponectin expression in larger fat cells. In addition, gene
transcription factors help regulate adiponectin, and this crucial
hormone is critical for supporting insulin sensitivity.
Weight Loss Supplements
An enzyme called glycerol-3-phosphatedehydrogenase is critical for
synthesizing fatty acids in our bodies. Suppressing this enzyme helps
reduce the amount of glucose (sugar) in our bloodstream from being
converted into fatty acids.
Weight loss utilizing diet modification, supplements, hormones or
drugs usually functions via a single mechanism. Adipocytes (fat cells),
on the other hand, possess numerous means to ensure their survival. An
extract from a West African plant called Irvingia has been shown to help
maintain healthy body weight in four ways:*
Weight Management: Reversing Leptin Resistance
Fat cells produce C-reactive protein, a pro-inflammatory compound
that leads to “leptin resistance.” Overweight people given Irvingia have
lower levels of CRP, and therefore less CRP is able to block the
activity of leptin. Leptin is important in weight management
because it promotes the breakdown of fat in adipocytes and tells the
brain to turn off chronic hunger messages.
Hormones: Increasing Adiponectin
Large fat cells secrete less adiponectin, and adiponectin is a
crucial hormone that helps support insulin sensitivity as well as
cardiovascular health. Overweight people given Irvingia show markedly
increased adiponectin levels.
Body Fat: Inhibiting the Fat Converting Enzyme
An enzyme called glycerol-3-phosphate dehydrogenase facilitates the
conversion of glucose into triglycerides that increase adipocyte size.
Irvingia inhibits glycerol-3-phosphate dehydrogenase, thus reducing the
amount of glucose (sugar) that is converted to fat in the body.
Diet: Reducing Carbohydrate Absorption
In order for carbohydrates to be fully absorbed, they must be broken
down in the digestive tract by the amylase enzyme. Irvingia inhibits
amylase, and thus reduces the amount of ingested starches that will be
absorbed as sugar.
Several studies demonstrate the weight loss
properties of Irvingia.1 In
the largest placebo controlled human study, those taking Irvingia lost
28 pounds over a 10-week period compared to only up to 3 pounds in the
placebo group.2 The study
participants did not alter their diet.*
Based on impressive human data, a dose of 150 mg of Integra-Lean™
Irvingia taken twice a day is all that was needed to achieve
unprecedented clinical results.
This supplement should be taken in conjunction with a healthy diet
and regular exercise program. Results may vary.