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Life Extension Mix with Extra Niacin

By: Life Extension

UPC Code: 737870155737

Price: $73.50

 

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Life Extension Mix with Extra Niacin
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Life Extension Mix™ Tablets with Extra Niacin

Life Extension Mix™ contains 94 unique vegetable, fruit, herbal extracts, amino acids, vitamins, and minerals. This state-of-the-art multinutrient formula has been updated numerous times since its launch in 1983. The Life Extension Mix™ formula is fortified with botanical extracts that help maintain healthy cells via physiological processes. Consumption of these types of plants is being recommended based on research emanating from the world’s most prestigious medical centers. The latest Life Extension Mix™ formula contains upgraded forms of chromium and folate, and a new ingredient called C3G, an antioxidant derived from blackberry and blackcurrant extracts which has been shown to support eye health, especially in low light conditions

Antiaging benefits of pterostilbene

Life Extension Mix™ includes trans-pterostilbene. This compound, found naturally in blueberries and grapes, has been shown to have beneficial antiaging effects on gene expression and to promote healthy cognitive function. According to Dr. Agnes Rimando, a leading expert in the biology of stilbenes (resveratrol, pterostilbene and other related compounds), "Stilbenes have diverse pharmacological activities which include enhanced insulin sensitivity, and increased lifespan."

Pyridoxal 5’-Phosphate

When sugars react with your body’s proteins, the result is the formation of non-functioning cross-linked structures, called advanced glycation end products (AGEs).3 While glycation is a normal consequence of aging, it is far from desirable.  In fact, similar glycation or "browning" reactions (called the Maillard reaction) occur in cooking meat when proteins combine with the sugars present. This same "cooking" process happens at a slower rate to your body’s proteins!

The blurring of our eye lens with aging is a result of a lifetime of glycation reactions. Glycation is also associated with arterial blood flow problems and long-term kidney issues.11-13 The pathological effect of glycation can also be seen outwardly in the form of cross-linked proteins in senescent skin.

Pyridoxal 5’-phosphate is the metabolically active B6 that has been shown to protect against protein and lipid glycation reactions.  Life Extension Mix™ provides 100 mg of pyridoxal 5’-phosphate in each daily dose.

Standardized pomegranate extract

The pomegranate extract contained in Life Extension Mix™ is standardized to provide the biologically active punicalagins that are so unique to this fruit. Pomegranate punicalagins are 100% water-soluble and have shown a remarkable 95% absorption rate.  When tested against popular antioxidant food extracts, pomegranate demonstrated one of the most potent free radical-suppressing effects. This means that pomegranate punicalagins not only absorb much better than other natural antioxidants, but they also have a superior antioxidant capacity.

Peer-reviewed published human studies show that pomegranate helps maintain healthy cardiovascular function by enhancing the endothelial nitric oxide synthase bioactivity, and inhibiting the oxidation of LDL cholesterol.  Pomegranate also has the unique property of helping to maintain healthy DNA structure in the prostate cells.  The daily dose of Life Extension Mix™ provides the equivalent of consuming up to 2.6 ounces of pomegranate juice— but without the sugar calories.

Standardized blueberry extracts

Blueberry anthocyanins are potent natural antioxidants that have demonstrated properties that extend well beyond suppressing free radicals.

For instance, blueberries have been shown to not only improve memory but to also undo some of the age-related changes seen in aging neurons. One study showed that the ability of blueberries to suppress free radical damage in the brain was analogous to long-term calorie restriction.  These findings hint that blueberries might be able to reverse certain aspects of brain aging!

Blueberry’s other active constituent (pterostilbene) promotes healthy lipid and glucose levels for those already within normal range.30,31 Even more exciting is that these blueberry constituents (pterostilbene and anthocyanins) may help protect DNA structure.  Life Extension Mix™ provides the standardized blueberry extracts that provide the most active constituents found in this health-promoting fruit.

Standardized green tea extract

Life Extension introduced green tea extract as a supplement in 1993 based on epidemiological studies showing that people who consumed green tea had lower incidences of common age-related problems.  Over the past 14 years, an enormous volume of positive studies has been published about the health benefits of green tea.

Scientists have looked at the active polyphenol constituents of green tea and have found that they possess remarkable biological activities that include inhibiting LDL oxidation and neuronal peroxidation, while maintaining healthy DNA structure.

Life Extension Mix™ contains 325 mg of a decaffeinated green tea extract that is standardized to provide 98% of the active polyphenols that scientists attribute to green tea’s multiple health benefits. The amount of polyphenols, especially epigallocatechin-3-gallate (EGCG), in Life Extension Mix™ is equivalent to drinking about three to four cups of green tea per day.

Standardized vegetable extracts

Luteolin is a flavonoid found in parsley, artichoke, basil, celery, and other foods. When measured against 27 other flavonoids, luteolin provided one of the highest levels of DNA protection.41 One favorable mechanism of luteolin is its ability to inhibit oxidative damage to cellular DNA. Another unique benefit is luteolin’s ability to suppress excess levels of dangerous inflammatory cytokines such as interleukin-6 and interleukin 1b.  Life Extension Mix™ contains a standardized dose of 8 mg of luteolin, a dose that emulates the benefits seen in published scientific studies.

Broccoli is touted as one of the most important vegetables to maintain healthy DNA gene structure. Broccoli contains several active constituents, with sulforaphane being the most significant because of its unique detoxification and DNA-protecting effects. Life Extension Mix™ provides a concentrated broccoli mixture that provides standardized extracts of sulforaphane and glucosinolates, two compounds attributed to broccoli’s multiple protective benefits. Broccoli is also a natural source of gene-protecting chlorophyll.

D-glucarate is a botanical extract found in grapefruit, apples, oranges, broccoli, and Brussels sprouts. D-glucarate effectively supports a detoxification process that helps to remove DNA toxins from the body. The daily dose of Life Extension Mix™ provides 200 mg of D-glucarate.

Lutein, an extract found in corn and in leafy greens such as kale and spinach, has been shown to help maintain critical pigments in the eye macula.  The carotenoid alpha carotene has demonstrated antioxidant activity greater than beta-carotene, whereas lycopene from tomatoes has shown potent effects in helping to maintain DNA structure and protecting against LDL oxidation.  Life Extension Mix™ contains 60 times more lutein and 10 times more lycopene than popular one-per-day multivitamins. Most multivitamin supplements provide no vegetable extracts whatsoever.

Standardized fruit extracts

In addition to standardized pomegranate and blueberry extracts, Life Extension Mix™ is also fortified with fruit extracts such as bilberry, grape seed, grape skin, and citrus bioflavonoids to provide healthy circulation throughout the body and maintain healthy DNA.

Scientists have long touted the multiple benefits of fruits such as blueberry, blackberry, cranberry, plums, elderberry, persimmon, and cherry. Life Extension Mix™ provides a customized blend of these and other fruits that result in multiple favorable effects in the body, according to numerous studies.

Olive oil consumption is one of the important factors behind the health benefits of the "Mediterranean Diet."  Researchers have discovered that there are up to 300 times more polyphenol compounds in olive water compared to olive oil.  Olive polyphenols have been the subject of numerous in vitro, in vivo, and human studies pointing toward their benefits in many different areas, including protecting against LDL oxidation, suppressing free radicals, and stabilizing cell membranes.  Life Extension Mix™ contains a potent olive extract standardized to provide the best-documented polyphenol, hydroxytyrosol.  The amount of hydroxytyrosol in the daily dose of Life Extension Mix™ is equivalent to drinking more than one ounce of virgin olive oil a day.

Sesame lignans enhance the effects of vitamin E

Sesame and its lignans have a broad range of applications in human health. This includes increasing human tissue levels of gamma-vitamin E by facilitating carrier proteins in the liver to deliver nutrients to cells throughout the body.

Sesame lignans increase the beneficial effects of fish oils and help maintain already-normal cholesterol/LDL levels in humans.  Life Extension Mix™ provides 10 mg sesame lignan extract to supply the direct benefits of the lignans, and augment the effects of vitamin E and other nutrients in the body such as gamma-linolenic acid (GLA).

Maintaining healthy blood glucose levels

Chromium, along with magnesium and biotin, are nutrients required to maintain healthy blood sugar for those already within normal range. In addition to a well-absorbed form of magnesium and high-potency biotin, Life Extension Mix™ provides 500 mcg chromium from Crominex® 3+, a highly stable and biologically active form of the mineral blended with Capros® amla and PrimaVie™ shilajit.  A review of studies showing benefits of chromium supplementation reveals that doses exceeding 200 mcg a day are required for optimal effects.

High-potency vitamin D3

Doctors used to be concerned that too much vitamin D could be toxic. Over the past few years, however, an increasing body of evidence indicates that it takes much higher doses of vitamin D (perhaps over 10,000 IU/day) to result in toxicity in a healthy person.

The concern expressed by researchers today is that fear of vitamin D toxicity is keeping many people from supplementing with enough vitamin D, which is critical for maintaining bone density and maintaining healthy cell division.

As a matter of fact, a recent review in the New England Journal of Medicine suggested recommended intakes for vitamin D are inadequate and need to be increased to at least 800 IU of vitamin D3 per day.81 Currently, most experts in the field believe that intakes of between 1,000 and 4,000 IU for adults will lead to a more healthy level of serum 25(OH)D, at approximately 32–70 ng/mL.

Life Extension recommends that healthy adults supplement each day with at least 1,000 IU of vitamin D. Elderly adults may benefit from higher doses such as 2,000 IU daily, and even up to 5,000 IU daily.

In response to this research showing that even those who take standard vitamin D supplements are not obtaining adequate amounts, Life Extension Mix™ provides 2,000 IU of vitamin D3 per daily dose.

A complete multinutrient formula

Life Extension Mix™ saves time and money by combining the most popular nutrient supplements into one product, eliminating the need to take separate B-complex, vitamins C and E, mineral supplements, and much more that would be required to achieve the same effects.

Life Extension Mix™ supplies the most powerful antioxidants, including water- and fat-soluble vitamin C, vitamin E, and plant extracts that help protect against cellular DNA damage. Other ingredients enhance beneficial DNA methylation patterns, help maintain glycemic control, and help prevent the oxidation of LDL that contributes to the buildup of deposits in the endothelial lining.

Life Extension Mix™ is the cornerstone of a comprehensive supplement program because it provides so many well-studied nutrients. If you are on a budget, the Life Extension Mix™ provides the best "cost-per-milligram" value.

The Life Extension Foundation Buyers Club mandates that the ingredients in Life Extension Mix™ come only from premium-quality suppliers. These premium companies charge more for their vitamins and trace elements, but the purity of these substances greatly exceeds that of the lower cost generic versions that are so prevalent in the vitamin industry.

Supplement Facts

Serving Size 9 tablets (per day)

Servings Per Container 35

Amount Per Serving

Vitamin A (as 90% Betatene®1 D. salina natural beta-carotene with mixed carotenoids and 10% acetate)

5000 IU

Vitamin C (as calcium ascorbate, ascorbic acid, ascorbyl palmitate, magnesium ascorbate, niacinamide ascorbate, and acerola extract)

2000 mg

Vitamin D3 (as cholecalciferol)

2000 IU

Vitamin E (as D-alpha tocopheryl succinate)

400 IU

Thiamine (vitamin B1) (as thiamine HCI)

125 mg

Riboflavin (vitamin B2) (with 2 mg riboflavin 5’-phosphate coenzyme)

50 mg

Niacin (vitamin B3) (as 58% niacinamide, 40% niacin, 2% niacinamide ascorbate)

862 mg

Vitamin B6 (as 100 mg pyridoxal 5’-phosphate coenzyme and 5 mg pyridoxine HCI)

105 mg

Folate [from (Citrus limon) extract (peel)]

400 mcg

Vitamin B12 (as 42% cyanocobalamin, 42% hydroxylcobalamin, 16% ion exchange resin)

600 mcg

Biotin

3000 mcg

Pantothenic acid (as D-calcium pantothenate with 5 mg pantethine)

600 mg

Calcium (as calcium ascorbate, D-calcium pantothenate, Calcium D-Glucarate2)

218 mg

Iodine (as potassium iodide)

150 mcg

Magnesium (as magnesium oxide, citrate, glycinate taurinate, arginate, ascorbate)

400 mg

Zinc (as OptiZinc®3 zinc monomethionine, zinc succinate)

35 mg

Selenium [as 50% Se-Methyl L-Selenocysteine, 25% L-selenomethionine (yeast free) (SelenoPure™4), and 25% sodium selenate]

200 mcg

Copper (as copper bisglycinate chelate)

1 mg

Manganese (as manganese gluconate)

1 mg

Chromium [as Crominex®5 3+ chromium stabilized with (Capros® standardized Phyllanthus emblica extract (fruit) and PrimaVie™ purified and standardized Shilajit)]

500 mcg

Molybdenum (as sodium molybdate)

125 mcg

Potassium (as potassium chloride)

37.4 mg

N-acetyl-L-cysteine (NAC)

600 mg

Taurine

200 mg

Inositol

250 mg

Phosphatidylcholine (from soy)

150 mg

Choline (as choline bitartrate)

120 mg

Boron (as boron citrate/aspartate/glycinate complex)

3 mg

Ascorbyl palmitate (fat-soluble vitamin C)

250 mg

para-Aminobenzoic acid (PABA)

200 mg

Trimethylglycine (TMG) (as betaine anhydrous) (from sugar beets)

100 mg

Citrus bioflavonoid complex (Citrus aurantium L.) (peel and fruit) [std. to 50% hesperidin (100mg)]

200 mg

Broccoli sprout concentrate (A proprietary blend of broccoli sprout concentrates and Calcium D-Glucarate2) (providing glucosinolates, sulforaphane, D-3T, and PEITC)

525 mg

Calcium D-Glucarate2

200 mg

Decaffeinated Green tea (Camellia sinensis) extract (leaf) [standardized to 98% polyphenols (318.5 mg) and 45% Epigallocatechin gallate (EGCG) (146.25 mg)]

325 mg

Acerola (Malpighia punicifolia) extract 4:1 (berry)

300 mg

Ginger (Zingiber officinale) extract (root) [standardized to 5% gingerols (10 mg)]

200 mg

HiActives 100% fruit/berry complex (A proprietary blend of concentrated blackberry, blueberry, cherry, cranberry, elderberry, persimmon, prune powders)

200 mg

Wild Blueberry (Vaccinium angustifolium) standardized anthocyanin extract (fruit)

150 mg

Milk thistle (Silybum marianum) extract (seeds) [standardized to 85% silymarin (85 mg)]

100 mg

POMELLA®10 Pomegranate (Punica granatum) extract (fruit) [std. to 30% punicalagins (25.5 mg)]

85 mg

Bilberry (Vaccinium myrtillus) extract (fruit) [standardized to 36% total anthocyaninins (10.8 mg)]

30 mg

Leucoselect®6 grape seed (Vitis vinifera) (seeds) extract [std. to 95% proanthocyanidins (23.75 mg)]

25 mg

BioVin®7 grape (Vitis vinifera) extract (whole grapes) [std. to 95% proanthocyanidins (23.75 mg)]

25 mg

Bromelain (from pineapple) (Ananas comosus) (stem) (2400 gelatin digestive units per gram)

15 mg

Lutein (purified concentrate from marigold flowers) (Tagetes erecta) (providing 465 mcg trans-zeaxanthin)

15 mg

Olive juice (Olea europea) extract (fresh fruit) [std. to 15% polyphenols (1.875 mg)] (providing hydroxytyrosol, tyrosol and oleuropein)

12.5 mg

Sesame seed (Sesamum indicum) lignan extract

10 mg

Luteolin (high purity luteolin, as Pureolin™8)

8 mg

Lycopene (from Lyc-O-Mato®9 natural tomato extract)

3 mg

Cyanidin-3-glucoside (C3G)

1.25 mg

trans-Pterostilbene (as pure Pterospan™11 and SMART™11 pterostilbene)

0.5 mg

 

Other ingredients: dicalcium phosphate, stearic acid, microcrystalline cellulose, maltodextrin, vegetable stearate, croscarmellose sodium, silica, pharmaceutical glaze.

 

Contains soybeans. Contains corn and sesame.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), tree nuts, wheat, yeast, gluten, or rice. Contains NO artificial sweeteners, flavors, or colors.

 

Dosage and Use

Take nine tablets per day in divided doses with meals, or as recommended by a healthcare practitioner.

Temporary flushing, itching, rash or gastric distrubances may occur. Liver function testing is recommended when niacin is taken in excess of 500 mg daily. Those with gout or liver diseases should avoid taking high doses of niacin. Consult with your doctor before using this product if you are taking anticoagulant medications. Individuals consuming more than 2,000 IU/day of vitamin D (from diet and supplements) should obtain a serum 25-hydroxy vitamin D measurement. Vitamin D suppplementation is not recommended for individuals with hypercalcemia (high blood calcium levels). Individuals with in-born errors of copper metabolism (e.g. Wilson's disease) should avoid daily, chronic use of this product.







Disclaimer:   This website is for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site. These statements made in this website have not been evaluated by the Food and Drug Administration. The products offered are not intended to diagnose, treat, cure, or prevent any disease. If you believe that you may have a disease condition, please consult your healthcare practitioner immediately, and before using any dietary supplement product.

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