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The maitake mushroom (Grifola frondosa) is the
source of immune enhancing compounds that are being shown to offer
significant health benefits, including potential to prevent and assist
in the treatment of cancer. (see also www.naturalmedifaqs.com)
Maitake Gold 404™ is a proprietary maitake extract developed by Dr.
Hiroaki Nanba, the world's leading authority on maitake. In 1984, Dr.
Nanba identified a fraction of maitake that possessed a significant
ability to stimulate white blood cells known as macrophages (literal
translation "big eaters"). Dr. Nanba termed his discovery maitake
D-fraction. Further purification of the D-fraction yielded the
MD-fraction, which is even more bioactive than
the D-fraction. Any research references to the D-fraction also apply to
the purer and more potent MD-fraction.
The MD-fraction provides superior results over the D-fraction. The researchers found the group
given the MD-fraction experienced a significantly stronger inhibitory
effect on tumor growth than that of the group given the D-fraction. The
MD-fraction also exhibited stronger immune system potentiation compared
to the D-fraction. Both fractions have low toxicity and high safety.
It appears that the beta-glucans in the maitake MD-fraction actually
bind to receptors on the outer membranes of macrophages and other white
blood cells including natural killer (NK) cells and cytotoxic T-cells
(Tc), immune cells that are very important in protecting against and
fighting cancer because they attack tumor cells directly.
The binding of the beta-glucan triggers a chain reaction leading to
increased immune activity.
Beta-glucans from Maitake Gold 404 also stimulate production of white
blood cells within the bone marrow, the major area for white blood cell
production. Reduced bone marrow production increases risk of infection
and cancer. This benefits cancer patients undergoing radiation or