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The maritime pine tree is endogenous to the western Mediterranean region. Pycnogenol® is the trade name for the extract of the bark of the French maritime pine tree. This pine bark extract is one of the most potent antioxidant compounds ever discovered and considered by many experts to be the nutritional breakthrough of the 20th century.* Pycnogenol® works synergistically with Vitamins C and E to help your body assault free radicals.* Pycnogenol® also bolsters the immune system, helps improve circulation in legs (specifically in the veins and capillaries), supports the heart, nourishes the skin, and may help remedy the occasional discomforts of PMS.