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St John's Wort Extract 300mg

By: Life Extension

UPC Code: 737870351061

Price: $8.23


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St John's Wort Extract 300mg
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Capsule 60 $10.98 25 $8.23

St. John’s Wort Extract Caps (0.3% Hypericin)

300 mg, 60 capsules

St. John's Wort (hypericin extract) is a weak inhibitor of monoamine oxidase (MAO), which may destroy dopamine in the brain and lead to low spirits. It has also been shown to inhibit re-uptake of several neurotransmitters, including serotonin, dopamine, noradrenaline, GABA, and L-glutamate in the brain, and to reduce expression of interleukin-6. Each of these actions can contribute to alleviating low mood status by slowing the recycling of neurotransmitters needed for maintaining emotional balance. Flavonoids, hypericin, and pseudo-hypericin are the constituents thought to be associated with the benefits of St. John's Wort. In particular, hypericin appears to be the active ingredient.

Supplement Facts

Serving Size 1 capsule

Servings Per Container 60

Amount Per Serving

St. John's Wort (Hypericum perforatum) Powder Extract (leaf & flower) [std. for 0.3% (0.9 mg) hypericin]

300 mg

Other ingredients: rice flour, maltodextrin, gelatin.

Contains corn and rice.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, or gluten. Contains NO artificial sweeteners, flavors, colors, or preservatives.

Dosage and Use

Take one capsule once or twice daily on an empty stomach, or as recommended by a healthcare practitioner.


Side effects can include insomnia, vivid dreams, restlessness, anxiety, agitation, irritability, gastrointestinal discomfort, fatigue, dry mouth, dizziness, and headache. Do not use if taking digoxin unless under a doctor's care. When using St. John's Wort, avoid prolonged sunlight exposure. Concomitant use with oral contraceptives may decrease steroid concentrations, resulting in breakthrough bleeding and irregular menstrual bleeding. Effectiveness of antiretroviral drugs may be reduced.


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