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Alpha-lipoic acid is an antioxidant used in Europe to promote liver and nerve health, and confer protective benefits against oxidative
processes. Alpha-lipoic acid has been called the “universal” antioxidant because it boosts glutathione levels in cells and has
potent antioxidant actions.
Research has strongly implicated cellular oxidative damage caused by free radicals as a cause of many degenerative problems.
What makes alpha-lipoic acid so effective as an antioxidant is its ability to quench free radicals in both aqueous and lipid
environments. This means that the antioxidant activity of alpha-lipoic acid is working in the extra-cellular fluid and also within the
cell. It also has metal chelating ability, helping the body rid itself of accumulated ingested toxins.110-113
Alpha-lipoic acid also is a co-factor for some of the key enzymes (alpha keto acid dehydrogenases) involved in generating energy
from food and oxygen in mitochondria114-116 and thus plays a critical role in energy production within the cell’s
One of the most beneficial effects of alpha-lipoic acid is its ability to regenerate other essential antioxidants such as vitamins C
and E, coenzyme Q10, and glutathione, and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx). The
evidence is especially strong for the ability of DHLA (dihydro-lipoic acid, a reduced form of alpha-lipoic acid) to recycle vitamin E.
This is apparently achieved directly by quenching tocopherol radicals or indirectly by reducing vitamin C or increasing the levels of
ubiquinol (a derivative of CoQ10) and glutathione, that, in turn, helps regenerate tissue levels of vitamin E.114,117-119
In clinical studies to date with alpha-lipoic acid, there have been no reported serious adverse side effects, even at high doses.
Among the mild, reversible side effects found in some patients have been allergic skin reactions and possible hypoglycemia in
diabetics. Please note that the R-lipoic acid (see product in this section) provides a more biologically active form of lipoic acid than
alpha-lipoic acid at only a slightly higher cost.
Serving Size 1 capsule
Servings Per Container 60
Amount Per Serving
Biotin 2500 mcg
Alpha-Lipoic Acid 250 mg
Other ingredients: gelatin, water, rice flour, magnesium stearate.
Contains rice. This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree
nuts, wheat, yeast, gluten, or corn. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.
Dosage and Use
One capsule in the morning and one in the evening, preferably with food is suggested, or as recommended by a healthcare