Numerous clinical studies performed in Russia have documented the efficacy of Eleuthro as an adaptogen. In the late 1960’s and 1970’s studies were conducted in over 2,100 healthy people. These studies showed the Siberian ginseng increased the ability of the subjects to withstand stresses such as heat, noise, motion, exercise, and increase in workload. Subjects also experi- enced increases in mental alertness and work output.Siberian ginseng is a thorny shrub native to East Russia, Northeast China, Korea, and Japan. It is often confused with Panax ginseng, which is in the same family (Araliaceae) as Siberian (Eleutherococcus) ginseng. However, both are distinctly different plants. To help avoid this confusion, Europeans refer to Siberian ginseng as “eleuthero root”. During the 1950’s and 1960’s Russian scientists began to extensively study the constituents and activities of this plant. A new terminology was about to be born, as scientists studied sub- stances that were able to bring about an “increased non-specific resistance” to an organism. These substances and the plants that contained them were called “adaptogens”. An adaptogen is a substance that helps the body adapt to stresses of various kinds. It must be absolutely harmless. It must have a “non-specific” broad therapeutic spectrum of action. It must also have a normalizing action that brings an organism back to homeostasis. Through Russian research, Siberian ginseng became the model of an adaptogen.