Suggested Usage

Take 1 tablet per day on an empty stomach, or as directed by your qualified health care consultant.  

WARNING: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e.

Jarrow FORMULAS® SAM-e 400 is foil blister-packed to maximize stability and safety. DO NOT use if  outer seal of blister pack is broken.

Full Potency 400 mg SAM-e is derived from 800 mg of SAM-e tosylate disulfate.

For best results, use with Jarrow FORMULAS® JarroSil™, the  biologically Activated Silicon™.

Product Highlights

• Enteric-Coated Pharmaceutical Grade SAMe
• Central biochemical building block
• #1 SAMe Product in Dollars Sales†
• 68-80% Active S,S Form
• Made Naturally By Fermentation
• Individually Blister-Packed

† #1 in Dollar Sales, according to SPINS, a market research and consulting firm for the Natural Product Industry (SPINScan Natural, 52 Weeks Ending 11/29/08)

What does SAM-e 400 do?

Jarrow FORMULAS® pharmaceutical grade, stabilized SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Contains More of the Active S,S Form

Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e.  The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.  Jarrow FORMULAS® SAM-e is madenaturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.SAM-e has been clinically shown to have the following benefits:

Joint Strength

SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.*

Brain Metabolism

SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).*

Longevity

Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demethylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.*

Liver

SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.*

PRODUCT OF ITALY.

Store in a cool, dry place.

Keep out of the reach of children.