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Relax-All

Relax-All:  Powerful Combination for

Supporting Health of People with Muscle Soreness, Inflammation and Pain

We are a nation in pain.  If you one of millions of Americans who are are experiencing pain and/or waking up too much during the night, if you’re experiencing too much stress, too much muscle soreness, if you’re overusing medications for your health challenges and you want change, we have an important message. 

Painkiller abuse is rampant in America.  In the past decade, the number of prescriptions written in the United States for narcotic painkillers has risen an average of nearly 500 percent per drug, according to a report in the November 17, 2003 issue of USA Today.

“On one hand, that’s good news for the millions of Americans thought to suffer from inadequately treated pain,” observes the newspaper.  “But the dramatic rise in prescriptions also means that there are more pills than ever available to people likely to abuse them, rather than use them for medical purposes.  Unfortunately, it’s nearly impossible to predict who will end up abusing or even becoming addicted to narcotic painkillers.  Radio talk-show host Rush Limbaugh—back on the job Monday after a month in rehab—and rock singer Courtney Love would appear to have little in common except their celebrity and their recently reported problems with the prescription painkiller OxyContin.”

You might not think you know anyone who is using or overusing painkillers.  But that’s probably because such addictions and overuse syndromes frequently are not even recognized by the abuser and, if they do sense their addiction, it is often kept secretive, either from embarrassment and/or because of illegalities associated with procuring such drugs (e.g., doctor shopping). 

Nonetheless we are a nation in pain.  Not all the time and not all of us.  But a lot of us are in pain some, most or all of the time.  These distressing facts tell the story:

§         One in four Americans experience significant pain.  Be it headaches, backaches, or cancer-associated pain, pain is second only to upper respiratory infections (colds and flu) for reasons to visit a doctor.

§         Pain causes lost days at work—a greater number on an annual basis than cancer and heart disease combined.

§         More than 25 million Americans suffer chronic, disabling, painful low back pain and approximately 65 to 80 percent of the population will be afflicted with low back pain at some point during their lives.[i], [ii] 

§         Some 20 million Americans have arthritis, most of which is osteoarthritis, but about fifteen percent have inflammatory arthritis, including rheumatoid, psoriatic, and ankylosing spondylitis.   

§         More than one-third of Americans carry greater than twenty percent excess weight, and hence suffer degenerative wear and tear on weight bearing joints, particularly the knees.  Morning stiffness, activity-based grinding, and just chronic aching becomes their lot in life.  The excess weight results in degenerative joint disease. 

§         Chronic fatigue is the third most common complaint for patients seeing physicians.  Pain drains and causes disruptive sleep particularly in older Americans.  With loss of healthful, restful sleep, hormonal  dysregulation occurs, and secondary depression. 

§         Judging from the sales of over-the-counter non-steroidal anti-inflammatory drugs (over eight billion dollars per year), we have a pill consuming society bent on drugging pain. 

§         People are increasingly reckless, population densities are greater, and cars are faster.  Hence, there are more car accidents.  The emergency response systems and Level I trauma units are patching up the injured better than before.  But even when the structural repair seems pretty good and the orthopedic and neurosurgery doctors sign off, rehabilitation is often limited.  Result:  more chronic pain.  Our legal system isn’t helping.  More pain means more gain, financial gain, that is, especially when establishing blame and damages often takes years.

§         The American diet is worsening, not improving.  There is more high fat, more additives, and more calories everywhere.  Our diet is not protecting us from, but rather inflicting further, pain.  

§         Sport injuries are also taking their toll on Americans.  Our pursuits are becoming more daring, more reckless, and more injury-prone.

§         Cancer is increasing, now striking greater than one in three Americans.  The pain of chemotherapy, radiation or surgery is all together too real.

What it All Means

Hopefully, these facts will alert you and not scare you.  Pain can be avoided if you’re lucky; it can be mitigated and sometimes eliminated if you’re smart.  If you are not so lucky, there are potential ways to eliminate or at least manage pain to give you back your life so that you no longer feel strangled by pain. 

The problem here is too many people are using non-steroidal anti-inflammatory drugs (NSAIDs), narcotics, or muscle relaxants that can become addictive, pose complications (especially gastrointestinal bleeding), or simply impair your ability to function during waking hours.

In the case of muscle soreness, inflammation, and pain—the combination of Serra-Trol with serrapeptase and Relax-ALL is definitely worth considering for efficacy, quality, safety, and pricing.  Let’s look at how Relax-All can help with muscle soreness and pain:

One of the major ways this formula works is to accentuate the positive muscle-relaxing effects of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which, in turn, influences the levels of two other neurotransmitters, dopamine and serotonin, producing a relaxation effect. 

Take phenibut (originally known as phenigamma), one of the key ingredients in the innovative Relax-All formula.  This derivative of GABA crosses the blood-brain barrier much more ably than GABA itself.[iii]   Phenibut not only provides a sedative effect but also muscle relaxation similar but milder and more safely than diazepam drugs.[iv]  Meantime, valerian is a medicinal herb that produces anxiolytic and sedative effects also via GABA mechanisms.  Finally, l-theanine has clinically shown to create a sense of relaxation via at least two different mechanisms.  First, this amino acid directly stimulates the production of alpha brain waves, creating a state of deep relaxation and mental alertness similar to what is achieved through meditation. Second, it is involved in the formation of GABA.

Magnolia bark with its phytochemicals magnolol and honokiol also offers powerful muscle relaxant activity.[v]  According to the authoritative website supplementwatch.com, “Numerous animal studies have demonstrated honokiol to act as a central-nervous-system depressant at high doses, but as a non-sedating anxiolytic (anti-anxiety and anti-stress) agent at lower doses.  This means that a small dose of honokiol, or a magnolia bark extract standardized for honokiol content, can help to ‘de-stress’ you without making you sleepy, while a larger dose might have the effect of knocking you out.  When compared to pharmaceutical agents such as Valium (diazepam), honokiol appears to be as effective in its anti-anxiety activity, yet not nearly as powerful in its sedative ability. These results have been demonstrated in at least half a dozen animal studies and suggest that magnolia-bark extracts standardized for honokiol content would be an appropriate approach for controlling the detrimental effects of everyday stressors without the tranquilizing side effects of pharmaceutical agents.”

Jujube, also known as zizyphus, a sweet and mild Chinese herb has mild sedative action.  It is a nervine tonic highly reputed for insomnia that is caused by nervous exhaustion and anxiety, heart palpitations, restlessness, and excessive sweating. 

Magnesium acts as a natural tranquilizer and can help reduce tremors and cramps. Yet, the typical American diet provides only one-third to half of daily requirements established for magnesium. Deficiencies result in nervousness, irritability, muscle cramping, mental and physical fatigue. Magnesium deficiency causes increased levels of adrenaline, which can lead to a feeling of anxiety

Calcium is a natural tranquilizer that works with magnesium.  A calcium deficiency produces muscle spasms and cramps, anxiety, nervousness, irritability, insomnia and headaches, among other symptoms.

The Best Non-prescription, Natural Muscle Relaxation Formula

With Serra-Trol and Relax-All, MRM has come up with a great one-two combination for not only supporting the health of people with undue inflammation and pain but also for people experiencing the kind of typical muscle soreness associated with athletic pursuits, over-activity, stress, and some types of overuse syndromes.  These are not drugs.

When we began learning about Relax-All, we realized this formula is a BIG DEAL. 

 

 


 

[i]Brown, R.L., et al.  “Chronic opioid analgesic therapy for chronic low back pain.”  Journal of the American Board of Family Practice, 1996; 9(3):  191-204.

[ii]Wittenberg, R.H., et al.  “Injection treatment of non-radicular lumbalgia.”  Orthopade, 1997; 26(6):  544-552.

[iii] Lapin, I.  CNS Drug Rev, 2001 Winter;7(4):471-81. “Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug.”

[iv] Shulgina, G.I.  “On neurotransmitter mechanisms of reinforcement and internal inhibition.”  Pavlov J Biol Sci, 1986;21(4):129-140.

[v] Watanabe, K., et al.  “Studies on the active principles of magnolia bark.  Centrally acting muscle relaxant activity of magnolol and honokiol.”  Naunyn Schmiedebergs Arch Pharmacol, 2003;368(4):262-269. Epub 2003, September 18.


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